Gamma-hydroxybutyrate (GHB) is a central nervous system depressant. Effects can vary, and combining it with alcohol or other sedatives can be especially dangerous.
Health effects and risks
GHB can cause drowsiness, confusion, loss of coordination, unconsciousness, slowed breathing, coma, or death. A person who cannot be awakened, has a seizure, or is breathing abnormally needs emergency help. Call 911; do not leave the person alone.
Testing and next steps
Drug screens vary by specimen and by the substances listed on a test’s panel. Check the instructions and panel before selecting a test; do not assume every product detects this substance. A home screen is preliminary. For more on specimen types, read Drug Testing Methods; for a preliminary positive result, read Unexpected or Preliminary Positive Results. The Substance Information hub lists the current staging test options.
Sources and support
See the National Institute on Drug Abuse’s Commonly Abused Drugs chart for a general overview. For confidential U.S. treatment referrals, contact SAMHSA’s National Helpline at 1-800-662-HELP (4357). Call 911 for a medical emergency.
